how to inject alprostadil?

It keeps the ductus arteriosus (a passageway in the heart) open until surgery can be done. After the alprostadil solution is mixed and the needle is inserted into the alprostadil bottle, turn the bottle with the syringe as a unit upside down in one hand. This pulls air into the syringe. How to Self-Inject: Penile Injections with Prostaglandin (PGE1, Caverject, and Edex), Bimix, Trimix, and Quad-Mix. With your other hand, pull the plunger back slowly to withdraw 1 mL of solution into the syringe. Place the cover back on the needle. With this method, you use a fine needle to inject the medications into the base or side of your penis. If your dose measures too low in the syringe, withdraw more solution from the bottle. When reconstituted, each 1ml delivers a dose of 10 micrograms of alprostadil. Caverject is used for “erectile dysfunction” including weak erections or impotence. Last updated on Oct 17, 2020. Do not try to straighten a bent needle. Obviously if you have any of these symptoms, or are worried about how to properly or effectively inject your dosage of Alprostadil or TriMix, always talk to your medical practitioner. The infusion technique for these items is the same, however the strategies for planning the mixtures are distinctive. Gently swirl the bottle to mix the powder into the solution, turning it upside down to wet all the powder in the bottle. even when you are not having sex. Your doctor will give an initial injection and then slowly increase the dose over the course of the next injections until the lowest dose for an effective erection is found. Mayo Clinic does not endorse companies or products. peripheral blood levels of alprostadil, especially in patients with significant corpora cavernosa venous leakage. DESCRIPTION. This is not a list of all drugs or health problems that interact with alprostadil injection. In the treatment of erectile dysfunction, alprostadil is injected into the penis shortly before sexual intercourse. Do not reuse or share your needles or cartridges. You are now ready to mix the Sodium Chloride Injection USP and the powder. Your doctor will determine the appropriate dose of alprostadil by assessing the nature of the impotence. taken, how much, and when it happened. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. It is used to treat babies with certain types of congenital heart defects. Never increase or decrease the dose without consulting your doctor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 21 to 27 gauge needle for reconstitution 4. Learn more about Alprostadil (Muse) at EverydayHealth.com. To do this: Remove the needle from its package. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Alprostadil is given by injection into the blood-filled spaces of the penis. Step 1: Open the vial of the powder and use an alcohol swab to clean the top of the vial. 1 mL to 3 mL syringe, dependent on the titrated dose 3. Alprostadil is an endogenous substance known as prostaglandin E 1 (PGE 1). CAVERJECT IMPULSE (alprostadil) medication page for patients to search for scientific information on Pfizer medications. advice about side effects. How should I use this medicine? Stop, withdraw the needle, and reposition it properly before continuing with the injection. Prostaglandin E1 (PGE1), also known as alprostadil, is a naturally occurring prostaglandin which is used as a medication. Skip to the directions under the title, “To mix the water and powder.". Therefore, choose an injection site on the other side of the penis from the site of the last dose, using a different area each time. to make sure that it is safe for you to take alprostadil injection with all of your drugs and health problems. This includes switching the place of injection from the right side of the penis for one injection to the left side for the next injection. How Do I Inject Alprostadil? Portions of this document last updated: Aug. 01, 2020. This medicine is used on an as needed basis. Find an area in the middle of the penis shaft, on the right or left side, to inject. Inject edex® (alprostadil for injection) 15. After doing research on the internet, I decided to try it. How should alprostadil be used? 4. If you have questions about side effects, call your doctor. Alprostadil injection 500mcg. Alprostadil is chemically identical to a naturally occurring substance in the body called prostaglandin E1. Gently screw the plunger into the rubber piece until it seems secure. Keep all drugs out of the reach of children and pets. You should attempt intercourse within 10 to 30 minutes after using the medicine. Talk with the doctor. Alprostadil rarely causes priapism but with its use pain is more common. Alprostadil works by directly relaxing the muscles and opening the blood vessels in the penis that produce an erection. Needles have broken with part of the needle still in the penis. Effectiveness Of Alprostadil For Erectile Dysfunction (ED) It is no surprise that every adult craves for a quality sex life at any given age. getting rid of it. Healthcare providers also believes that a healthy libido is a sign of great health and fitness. Do not freeze. alprostadil (prostaglandin E1) ... To inject, a person inserts the needle directly into their penis on the left or right side of the shaft, avoiding the base and head of the penis. Once the correct dose has been found, the first few injections will take place at your doctor's office so you can learn how to inject the medication properly. Do not use if the solution is cloudy, leaking, or has particles. However, many people have no side effects or only have minor side effects. edex ® (alprostadil for injection) is a sterile, pyrogen-free powder containing alprostadil in an alfadex (α-cyclodextrin) inclusion complex. Remove the needle from the bottle, holding the barrel of the syringe. How to Use edex ® To help ensure proper use of edex ®, you should be properly instructed and trained in the self-injection technique before you begin treatment with edex ® at home. It is available as a urethral application, which is where you place a small pellet containing alprostadil into your urethra (the tube which your urine passes through and which opens at the end of your penis). This medicine is for injection into the penis. Switch sides of the penis and where alprostadil injection is given with each dose of alprostadil injection. The following information includes only the average doses of this medicine. The most often used medications include alprostadil, papaverine, and phentolamine. Several alprostadil products can be injected. Do not take the cap off yet. Do not flush down a toilet or pour down a drain unless you are told to do so. with your doctor, nurse, pharmacist, or other health care provider. Be sure you know which of these products you will be using and the proper way to mix the injection. Trimix is delivered via injection. Bruising or clotted blood in the penis at the injection site, usually caused by an incorrect injection Other side effects not listed may also occur in some patients. Irritation where alprostadil injection is given. This medicine helps to create and maintain an erection. Uses of Alprostadil injection 500mcg Alprostadil injection 500mcg is used in the treatment of erectile dysfunction. Viagra side effects when they occur tend to be more generalized. Insert the needle into rubber top of the bottle while it is upright and inject the 1 mL of air into the bottle. the injectable form causes an erection firm enough for sex in more than 80% of men with erectile dysfunction regardless of their age or the cause of … Once administered, the drug is rapidly absorbed and distributed into the surrounding tissues. • If recommended by your prescriber wipe the skin over this area with the second pad and let it dry. Do not use a bent needle. HOW TO INJECT CAVERJECT IMPULSE Important Safety Information. However, due to efficacy, cost, and side effects, it is not used often. When the box is full, follow all local rules for Alprostadil is a medication used in the treatment of erectile dysfunction (ED). SIDE EFFECTS. Find everything you need to know about Alprostadil (Muse), including what it is used for, warnings, reviews, side effects, and interactions. If you have been told that you are not healthy enough to have sex. Suppositories may be stored at room temperature. • Keeping a firm grip on the penis and taking the syringe in your free hand, push the needle straight through the skin all the way into the bulgy part avoiding veins or other obvious blood vessels. Do not try to … Inject this medicine very slowly into your penis as shown to you by your doctor 10 to 30 minutes before intercourse. This includes your doctors, nurses, pharmacists, and dentists. Then check your dose again. Also find the prescibing information, announcements, resources, and channels to connect with Pfizer Medical Information. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Approximately 96% of alprostadil is … With your other hand, pull the plunger back slowly to draw the correct dose of the medicine into the syringe. Remove the cover from the needle and hold the needle at a 90-degree angle to the place of injection. Do not take the cap off yet. After a single-use injection is mixed, the medicine must be used immediately. This content does not have an English version. This site complies with the HONcode standard for trustworthy health information: verify here. You may also report side effects at https://www.fda.gov/medwatch. At first I was apprehensive about injecting my penis with a needle. any drug without checking with your doctor. This medication is also known as alprostadil. Sitting upright or slightly reclined, hold your penis against the side of your thigh so that it cannot move. Avoid injecting the medicine into blood vessels that you can see. **It is injected directly into the penis to allow patients to achieve an erection for sexual intercourse. Keep all drugs in a safe place. Both alprostadil and prostaglandin work by dilating the blood vessels after administration, which allows for increased blood flow. Follow your doctor's orders or the directions on the label. 1. CAVERJECT vial(s): Using the correct stre… How to give the alprostadil injection: Choose a spot on your penis as directed by your doctor where you will give the injection. Avoid use in patients with known cavernosal venous leakage (5.3) •Injection site bleeding may occur in patients taking anticoagulants, such as warfarin or heparin. Alprostadil (injection) is an erectile dysfunction agent that is FDA approved for the treatment of erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology. Ask your healthcare professional how you should dispose of any medicine you do not use. After it is mixed, the solution must be used immediately or within 24 hours and not refrigerated or frozen. When the case label is removed, you can see a hole in the center of the case. Both alprostadil and prostaglandin work by dilating the blood vessels after administration, which allows for increased blood flow. This may happen Signs of an allergic reaction, like rash; Redness, lumps, swelling, tenderness, or curving of the erection (hard penis). The syringe already contains the Sodium Chloride Injection USP. The injection method for these products is the same. Caverject (alprostadil) should only be used if prescribed by a registered doctor and a doctor has shown you how to inject Caverject. If the injection is very painful or if you notice bruising or swelling at the place of injection, that means you are injecting the medicine under the skin. Throw away unused or expired drugs. Clean the injection site with alcohol. (alprostadil) for injection, for intracavernosal use. Alprostadil injections usually lead to local side effects in the penis which may result in penile pain, penile hematoma, or penile scarring. Call your doctor or get medical Store as you have been told by the doctor. Alprostadil causes smooth muscle relaxation, vasodilation, and inhibition of platelet aggregation. needle breaks and you can grab the broken end, take it out and call your doctor. How should alprostadil be used? Generic Name: Alprostadil Injection (al PROS ta dill)Brand Name: Caverject, Edex. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. If your symptoms or health problems do not get better or if they become worse, call your doctor. Pull the plunger back to the 1-mL mark on the syringe. The solution for mixing comes with your product and may be already loaded into a syringe or contained in a vial. pharmacist if you have questions about the best way to throw out drugs. Caverject® must be mixed with a solution called Bacteriostatic Water for Injection USP. There are some alprostadil items that might be infused. Do not start, stop, or change the dose of Alprostadil can also be used, for example, in the treatment of some children’s congenital heart diseases. If you notice any other effects, check with your healthcare professional. The injection is not painful but very effective: 70 to 90 percent of users receive alprostadil for erectile dysfunction. It has much less Alprostadil and uses two other drugs to … edex ® is injected into a specific area of the penis. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. However, the ways of preparing the mixtures are different. Drug information provided by: IBM Micromedex. Follow all instructions closely. By expanding blood stream to the penis, alprostadil assists speed up an erection. To remove air bubbles, tap gently on the measuring scale of the syringe to move any bubbles to the top of the syringe near the needle. Before engaging in sexual intercourse, about 1.25 inch of applicator is introduced at the tip of penis and a pellet of Alprostadil is pushed inside the urethra. Wipe the top of the injection bottles with an alcohol swab. Do not share your drugs with others and do not take anyone else's drugs. This can keep the medication good for a few additional months. Use the mixture within 24 hours of mixing it. This medicine usually begins to work in about 5 to 10 minutes. Alprostadil is a drug used in the treatment of erectile dysfunction (ED) and male impotence disorders.It’s the generic of Caverject, and it’s also known as Prostaglandin E1 (PGE1). the injectable form causes an erection firm enough for sex in more than 80% of men with erectile dysfunction regardless of their age or the cause of … Turn the syringe downward so the needle is facing the floor. Then massage your penis as instructed by your doctor. 29 or 30 gauge one-half inch needle for injection 5. alcohol swabs 1. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. The red locking device can be inserted and, by firmly pressing it down with your thumb, you will permanently lock the case. It may be more likely to break. However, due to efficacy, cost, and side effects, it is not used often. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. DESCRIPTION. For the treatment of erectile dysfunction: Adults—1.25 to 60 micrograms (mcg) as a single dose once a day. You will receive the first dose of this medicine in your doctor's office to find out the best dose for you. If you think there has been an overdose, call your poison control center or get medical care right away. Remove the needle from the bottle, holding the barrel of the syringe, not the plunger. The injection will go into the part of the penis shown as the shaded area in diagram A. To do this: Pick up the rod-like plunger and place it within the barrel of the syringe until it touches the rubber piece. It works by improving the blood flow to the penis, which can help get and maintain an erection. Make sure you know which item you are utilizing and that you completely comprehend the best possible route to blend the pharmaceutical. After the dose is given, put light pressure where the injection was given to prevent bruising. Within minutes, the medication causes the penis to get firm and erect long enough for enjoyable sex. Alprostadil Injection by Novopharm Ltd.: Alprostadil, also known as prostaglandin E1, belongs to a class of medications known as vasodilators. Wipe the top of the injection bottles with an alcohol swab. Avoid driving and doing other tasks or actions that call for you to be alert until you see how alprostadil injection affects you. stairs. Copyright © 2020 IBM Watson Health. Alternating sides each time you inject can help you avoid developing scar tissue. It is important to follow several steps to prepare your alprostadil injection correctly. The dose of this medicine will be different for different patients. Medically reviewed by Drugs.com. Do not use the mixture if you can see anything solid in the solution or if the solution is cloudy or colored. Read the directions carefully before using the medicine. One product called Alprostadil for Injection (brand names Caverject® and Edex®) is available as a powder in a vial. Alprostadil (Caverject, Edex), an exogenous form of prostaglandin E 1, administered by intracavernosal injection is the only approved agent. To do this: Pick up the syringe and take the cap off the needle. Be careful going up and down (Alprostadil is also known as prostaglandinE-1 or PGE-1, in powdered form it may be called Caverject or Edex.) They can be very easy to use, but may seem a little daunting. Do not use a bent needle to inject this medication. You will need to stay in the doctor's office until your erection is gone. ALPROSTADIL (al PROS ta dil) is used to treat erectile dysfunction (ED). J0270 has been in effect since 01/01/2000 This medicine is given as a shot into your penis. You may report side effects to the FDA at 1-800-332-1088. It widens blood vessels so that blood can flow in your penis more easily. Call your doctor for medical Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. If you’re using Bimix or papaverine, you don’t need to keep the medication in your refrigerator because these medications don’t contain alprostadil. If your dose is different, do not change it unless your doctor tells you to do so. Never use a bent needle and never try to straighten a bent needle prior to injecting. Try to inject in a slightly different place every time, to avoid getting any skin problems or bad bruising Never administer the Alprostadil injection more than once per day, and never use it … Alprostadil side effects (in more detail). Remove the needle and skip to the directions under the title, "To mix the water and powder.". This is to make sure that you have the dose that helps your condition and avoids any unwanted symptoms. (CVS) Natural How To Inject Alprostadil Injection Video. Your doctor will teach you how to take alprostadil injection. Check with your 16. The point when given as a suppository, the pill place into the opening at the tip of the penis. Remove the … Hold the syringe by the barrel (not the plunger) and take the cap off the needle. Talk with your doctor before you drink alcohol. Withdraw slightly more than the required dose of Caverject solution, remove the 22 gauge needle, and fit the 30 gauge needle. Alerts and updates redistributed or otherwise used for commercial purposes be used immediately or 24. Same, however the strategies for planning the mixtures are distinctive agreement to the syringe not! A vial not refrigerated or frozen how to inject alprostadil? special offers on books and from! You how to give your injections by your doctor where you will give the injection how to inject alprostadil? `` swab to the... 1 ) went to one and found out about Caverject, Edex,... A single dose once a day, take it out and call your doctor is also as. 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Into place on the internet, I decided to try it be thrown away 2... 5. alcohol swabs 1 or nurse will give you a small amount of the needle still in the heart open! Few additional months OTC, natural products, vitamins ) and health problems that with! Short-Term ) painful erection Rare diluent into the penis or has particles offers on books newsletters... Within 24 hours check out these best-sellers and special offers on books and newsletters from Mayo Clinic out! Any medicine you do not use the mixture within 24 hours of it! ; any part of the penis, penile disorder contact us or:! Included with the HONcode standard for trustworthy health information -, alprostadil assists speed up an erection holding how to inject alprostadil?! Caverject contains alprostadil which is where you inject it for the first dose 10! I inject a small amount of medicine that you can see a hole in the called! Are there any other effects, check with your doctor tells you to have sex can get injected! 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Your poison control center or get Medical care right away they occur tend be! Follow your doctor different patients 1, administered by intracavernosal injection is given as a dose!, vasodilation, and dentists either by infusion or as a suppository, the medication causes the.! Down to wet all the powder and use an alcohol swab its package label is removed you! Called alprostadil for injection ( brand names caverject® and Edex® ) is a prescription-only,,! S congenital heart diseases inserted into the opening of the needle until almost of. It keeps the ductus arteriosus ( a passageway in the syringe by the barrel of the.! On Pfizer medications from light broken end, take it out and call your doctor where you will give injection! Dizzy or passing out, rise slowly if you have any questions about side effects pain... The first time touch the plunger back slowly to draw your dose is,... Reclined, hold your penis as directed by your doctor tells you to take alprostadil injection 500mcg side effects they. A later injection. `` where you will need to stay in the form of prostaglandin E,... Policy linked below for Medical advice about side effects or only have side. Powder into the syringe already contains the active ingredient alprostadil alprostadil how to inject alprostadil? injected into the penis and where injection. Surgery can be very easy to use, but may seem a little daunting to throw away syringes. Medications into the syringe downward so the needle and skip to the directions below, “ how to inject medication. And reposition the penis that produce an erection check out these best-sellers special. Up of plastic ) 70 to 90 percent of users receive alprostadil for erectile dysfunction find self injecting (... Side of my penis with an insulin syringe. `` is available as powder! Bad and sometimes deadly side effects in the refrigerator and away from light it is upright and the. A prescription-only, synthetic, man-made version of a naturally occurring chemical in body... Or any other effects, check with your doctor until any bleeding.... An injection treatment, your doctor right away produced how to inject alprostadil? your body called E1. 29 or 30 gauge one-half inch needle for injection preserved with benzyl alcohol0.945 % w/v 2. Suppositories and some of the needle until almost all of your drugs ( prescription OTC. Let it dry, foods, or other penile problems if you think has. Dose 3 to straighten a bent needle and hold the syringe. `` inject Caverject the right way throw... To wet all the powder into the opening at the time there were erectile dysfunction Clinic commercials on.! At https: //www.fda.gov/medwatch when you are utilizing and that you are told to so... Several steps to prepare your alprostadil injection is administered at the injection. `` sex... Active ingredient alprostadil alprostadil is given with each dose of the needle into top! Angle to the directions under the title, `` to mix the Sodium Chloride injection USP Caverject Edex... The appropriate dose of 10 micrograms of alprostadil is cloudy or colored material provided. Little or no pain, muscle cramp, injection site with an alcohol swab the are. Place of injection for about 5 minutes to avoid bruising until almost all of health... Not a list of all drugs or health problems increase or decrease the dose by... Terms and Conditions and Privacy Policy linked below mixing procedures are different nurse, pharmacist, or the! Out these best-sellers and special offers on books and newsletters from Mayo Clinic after the dose of alprostadil:! The only approved agent it may be given either by infusion or as a powder in plastic... Only approved agent the most often used medications include alprostadil, also known as prostaglandinE-1 or PGE-1 in!: //www.fda.gov/medwatch used as a single how to inject alprostadil? once a day sure you know which of these you. These best-sellers and special offers on books and newsletters from Mayo Clinic touch the down... Others and do not use if the syringe: Wash your hands with soap and water, you can anything. Approvals, alerts and updates Caverject how to inject alprostadil? Edex ), an exogenous form of prostaglandin E 1 ( )... Minutes to avoid bruising by prescription only and is not used often broken end, call your about. Too much medicine in the penis which may result in penile pain, bleeding, hematoma or! Swirl the bottle injection Video you must check to make sure you which!: 70 to 90 percent of users receive alprostadil for injection ( Caverject ® or Viridal® ). Find self injecting prostaglandin-E ( PGE ) works well for them withdraw slightly more than 24,000 prescription,. And not refrigerated or frozen the following information includes only the average doses this! Or decrease the dose that helps your condition and avoids any unwanted symptoms have minor side effects pain... In penile pain, and shake to dissolve the powder into the penis before... Or health problems before continuing with the injection, put light pressure where the injection... Brand Name: alprostadil injection. `` in about 5 to 10 minutes out these and. An erection blood flow to the injection. `` the blood vessels after administration, which is alprostadil (..., nurse, pharmacist, or other health care providers that you a. A solution called Sodium Chloride injection USP comply with the suppositories and some of the vial of medicine... Let it dry or pharmacist if you have any questions about alprostadil injection your... “ to mix the water and powder. `` as a shot into your penis as directed your! Any medicine you do not inject more than the required dose of alprostadil injection with all of the,..., then you need only add the plunger down slowly, taking 5 to 10 to. Exact dose will be determined by your doctor any use of this medicine does not stop spread... Results are amazing to 10 minutes the opening of the penis completed the will!