MicroRNA expression profiling was shown to be associated with tumour development, progression and response to therapy, suggesting their possible … Disease Glycomics Team, RIKEN‐Max Planck Joint Research Center, Global Research Cluster, RIKENWako, Japan. All papers selected for publication have passed a transparent and fair editorial peer-review process that ensures a reliable scientific literature. Open Access. This commentary explores why Japan may have, up to now, been spared an escalation of the SARS‐CoV‐2 infections. Alveolar macrophages produce interferons and activate interferon stimulated genes when challenged with influenza A virus or Sendai virus, but not when challenged with SARS‐CoV‐2, suggesting that its genomic RNA is undetectable for innate immune sensors. What are the prospects for the SARS‐CoV‐2 pandemic in Africa? EMBO Molecular Medicine is the top open access journal in the field of experimental medicine dedicated to science at the interface between translational and clinical research and basic life sciences. EMBO Molecular Medicine is a peer-reviewed, open access online journal dedicated to a new research discipline at the interface between clinical research and basic biology. EMBO Molecular Medicine Journal Impact Quartile: Q1. Pediatric Stem Cell Research Institute, Edmond and LiliSafra Children's Hospital, Sheba Medical Center, Ramat‐Gan, Israel. Research Article. Corresponding authors* affiliated with an eligible German institute or university can now publish their work Open Access in EMBO Molecular Medicine at no direct charge to the author with all OA-related costs being covered under the terms of the agreement. Kaposiform lymphangiomatosis (KLA) is a rare lymphatic anomaly primarily affecting the mediastinum with high mortality rate. EMBO Mol Med; EMBO Molecular Medicine Vols. Molecular characterization identifies ALDH1A3 as a pre‐treatment discriminator of pro‐malignant tumors that predicts response to therapy. rRv2626c‐CA, a macrophages‐targeted tetrapeptide‐conjugated protein composed of 9 amino acids of Rv2626c, is shown here to be the first therapeutic protein to regulate immune response and bacteria growth in the TLR4 signaling pathway for treatment of sepsis. Ewan M. Harrison . (Scientific image by Adam Grundhoff, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany), By Thomas Günther, Adam Grundhoff, Nicole Fischer, Melanie M. Brinkmann and colleagues. Mari Auranen. EMBO Molecular Medicine is the top open access journal in the field of experimental medicine dedicated to science at the interface between translational and clinical research and basic life sciences. Our journal is editorially independent of its publisher Wiley. Please see additional details on the online payment page when you submit your revised manuscript. Search for more papers by this author. CB, LGE and DEZ designed the study. The major goals of the organization are to support talented researchers at all stages of their careers, stimulate the exchange of scientific information, and help build a European research environment where scientists can achieve their best work. EMBO Molecular Medicine. # Contributed equally. Thus, the paper by Cavarelli et al. The quality of the journal is guaranteed by … Research Article. It is dedicated to the publication of the results of original, cutting-edge research in the field of Molecular Medicine and will be of interest to medical and basic scientists. EMBO Molecular Medicine is a broad scope journal dedicated to the interface between clinical research and molecular cell biology helping to forge new links between clinicians and molecular biologists. EMBO Molecular Medicine levies an Article Processing Charge (APC) of 3,850 EUROS (4,600 USD/GBP 3,300) plus tax, where applicable, for Research Articles, Reports or Resources accepted for publication. EMBO Molecular Medicine will continue to be a highly selective open access journal dedicated to research at the interface between clinical research and basic science. Neuropathic pain is characterized by hypersensitivity to temperature and touch as well as spontaneous outburst of pain. In this study we identified a cytochrome bd oxidase inhibitor ND‐011992 that together with Q203 forms a bactericidal drug combination against. EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications. EMBO is an organization of more than 1700 leading researchers that promotes excellence in the life sciences. The study demonstrates that patients with COVID‐19 experience a significant reduction of serum sphingosine‐1‐phosphate (S1P). EMBO as a basic life science organization is known for its commitment to excellence, recognition and fostering of scientific talent and last but not the least collegiality. 12 2020: v.12(1) 2020 Jan 9: v.12(2) 2020 Feb 7: v.12(3) 2020 Mar 6: v.12(4) 2020 Apr 7: v.12(5) 2020 May 8: v.12(6) 2020 Jun 8: v.12(7) 2020 Jul 7: v.12(8) 2020 Aug 7: v.12(9) 2020 Sep 7: v.12(10) 2020 Oct 7: Vol. At revision stage, authors are prompted by the system to fill in their funding and payment details. EMBO Molecular Medicine - インパクトファクター. EMBO Molecular Medicine articles are freely accessible to all via the Internet and are also deposited immediately upon publication, without embargo, to the Open Access repository PubMed Central. EMBO Molecular Medicine will continue to be a highly selective open access journal dedicated to research at the interface between clinical research and basic science. All papers selected for publication have passed a transparent and fair editorial peer-review process that ensures a reliable scientific literature. Metastasis is a major cause of morbidity and mortality in cancer patients. Virginia Quaresima, Matteo Naldini and Daniela Cirillo analyse the situation in this timely commentary. Author contributions. We encourage submissions of first-in-human studies and analyses of patient samples. EMBO Mol Med. Studies based on model organisms also fall within the scope of the journal, provided that the results presented are directly relevant to human disease. 1 to 12; 2009 to 2020; Vol. The major goals of the organization are to support talented researchers at all stages of their careers, stimulate the exchange of scientific information, and help build a European research environment where scientists can achieve their best work. Please check your email for instructions on resetting your password. EMBO Molecular Medicine is dedicated to the rapid publication of original, cutting edge research of interest to both medical and basic scientists. In exceptional circumstances charges may be reduced for authors who can provide evidence that they are unable to pay the fees. The isolation and characterization of renal cancer initiating cells from human Wilms' tumour xenografts unveils new therapeutic targets † Naomi Pode‐Shakked. This month's cover highlights the article SARS-CoV-2 outbreak investigation in a German meat processing plant by Thomas Günther, Adam Grundhoff, Nicole Fischer, Melanie M. Brinkmann and colleagues. 4 College of Pharmacy, University of Florida, Gainesville, FL, USA. We present a patient with KLA and significant disease burden harboring a somatic point mutation in the Casitas B lineage lymphoma (CBL) gene. CB, KA, TT, NX and XC performed experiments. Upon acceptance, the corresponding author will receive instructions by email for completing the relevant license forms. Modified Atkins diet induces subacute selective ragged‐red‐fiber lysis in mitochondrial myopathy patients. Jose A. Palacios and Michael D. Schneider, Heart to heart: grafting cardiosphere‐derived cells augments cardiac self‐repair by both myocytes and stem cells, EMBO Molecular Medicine, 5, 2, (177-179), (2013). Aberrant expression of nuclear matrix‐associated proteins (NMPs) has been shown to associate with tumor growth in various human cancers. Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC. This study describes the discovery and characterization of a novel TREM2 antibody, which induces protective microglial functions and provides a basis for the development of human antibodies with a similar mechanistic profile for treatment of Alzheimer's disease. Exploring the secrets of life. Results were published in the EMBO Molecular Medicine journal on 23 March. Department of Veterinary Medicine, University of Cambridge, Cambridge, UK. EMBO Molecular Medicine is supported by our academic Chief Editor, Prof. Philippe Sansonetti, nine academic Senior Editors and our broad and diverse advisory editorial board (https://www.embopress.org/page/journal/17574684/editors). EMBO Molecular Medicine is an open-access peer-reviewed medical journal covering research in molecular medicine. 29% scientists expect EMBO Molecular Medicine Journal Impact 2020 will be in the range of 11.0 ~ 11.5. doi: 10.15252/emmm.202012697. EMBO Molecular Medicine Volume 5, Issue 1. Whether you are currently performing experiments or are in the midst of writing, the following EMBO Molecular Medicine - Review Speed data may help you to select an efficient and right journal for your manuscripts. EMBO Molecular Medicine is a broad scope open access research journal dedicated to the interface between clinical research and molecular cell biology. The quality of the journal is guaranteed by the editorial and advisory boards, consisting of leading researchers in the field of molecular medicine, together with the commitment to scientific excellence and the professionalism of EMBO Editors. EMBO Press is a foundation signatory of the San Francisco Declaration on Research Assessment (DORA) pointing to flaws in the Journal Impact Factor and particular in its application to the assessment of the research output of individuals. This study identifies a peptide that can inhibit PICK1 and thereby interfere with insertion of excess glutamate receptor underlying the hypersensitivity in neuropathic pain. This study shows that SATB2, a key NMP, and its coactivator CBP critically contribute to glioblastoma (GBM) growth, suggesting SATB2/CBP is a therapeutic target. Metastasis is a major cause of morbidity and mortality in cancer patients. EMBO aims to define molecular biology in the broadest terms possible, encompassing research on the molecular mechanisms of life at all levels, from single molecules to organisms and ecosystems. According to standard scholarly practice, it is recommended to provide appropriate citation and attribution whenever technically possible. Med., ist eine wissenschaftliche Fachzeitschrift, die vom Wiley-Blackwell-Verlag im Auftrag der European Molecular Biology Organization als open access Online-Journal veröffentlicht wird. Oral delivery of the mitochondrial protonophore BAM15 markedly reduced weight gain and fat accrual while improving glycemic control. “The new Members have contributed to the success of research in the life sciences in Europe and around the world,” said EMBO Director Maria … The Journal Impact 2019 of EMBO Molecular Medicine is 10.280, which is just updated in 2020. This review offers a comprehensive overview of recent advances on models and mechanisms of SCLC metastasis. EMBO Molecular Medicine encourages applying due care in interpreting these numbers. The journal publishes articles under the Creative Commons Attribution CC BY 4.0 License. Processing of an accepted manuscript for publication can only proceed once the funding and payment details have been provided via the system and the licence to publish has been returned. The European Molecular Biology Laboratory is a powerhouse of biological expertise.. With 27 member states, EMBL currently employs 1800 people with more than 80 independent research groups covering the spectrum of molecular biology at six sites in Barcelona, Grenoble, Hamburg, Heidelberg, EMBL-EBI Hinxton and Rome. YCL, SVK and LGE critically reviewed the data and gave feedback. * You must be the submitting corresponding author and affiliated with a publicly or privately funded German research institution entitled under Projekt DEAL at the point of acceptance. Immunosuppressive myeloid cells (IMCs) are a prominent driver of immunotherapy resistance in colorectal cancer. 1.0 days. EMBO is an organization of more than 1700 leading researchers that promotes excellence in the life sciences. Yasuhiko Kizuka . Published in partnership with RUP and CSHLP. This comprehensive review discusses preclinical and clinical outcomes of remdesivir and other repurposed antiviral drugs against SARS‐CoV‐2. EMBO Molecular Medicine is a peer-reviewed, open access online journal dedicated to a new research discipline at the interface between clinical research and basic biology. EMBO Mol Med 1: 99-111, molecular biologists, clinicians and medical doctors. The authors use human intestinal explants to elucidate mechanisms of HIV transfer across the CE of the colon. EMBO as a basic life science organization is known for its commitment to excellence, recognition and fostering of scientific talent and last but not the least collegiality. Compared with historical Journal Impact data, the Journal Impact 2018 of EMBO … EMBO Molecular Medicine Volume 8, Issue 11. Journal Citation Reports (Clarivate Analytics, 2020). EMBO Molecular Medicine is an open access online journal published by Wiley-Blackwell on behalf of EMBO. The authors' moral rights are not compromised. This study identifies EP4 as a master regulator of IMCs and highlights blockade of EP4 as a novel therapeutic strategy for enhancing immunotherapy in colorectal cancer. Supporting Information is available at EMBO Molecular Medicine online. 4 College of Pharmacy, University of Florida, Gainesville, FL, USA. Shinobu Kitazume. All authors analyzed data and contributed to manuscript editing. This waiver removes legal barriers to the re-use and mining of research data. This study presents a novel therapy for treatment of obesity‐related diseases. EMBO Mol Med. EMBO Mol Med. Cancer of the colon is the third most common cancer in France, with nearly 40 000 estimated new cases in 2010. EMBO publishes five peer-reviewed scientific journals: The EMBO Journal, EMBO Reports, Molecular Systems Biology, EMBO Molecular Medicine, and Life Science Alliance. We aim to design and develop a humanized decoy antibody to block SARS‐CoV‐2 infection. Research Program of Molecular Neurology, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland. EMBO Molecular Medicine 10 November 2020 Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected Submissions of first-in-human studies and analyses of patient samples of remdesivir and other repurposed antiviral against. Of MRSA isolates with the novel mecA homologue mecC please read this editorial for a more detailed discussion [ EMBO... Publication have passed a transparent and fair editorial peer-review process that ensures a reliable scientific literature for News Views... Isolation and characterization of renal cancer initiating cells from human Wilms ' tumour xenografts unveils new targets... It is recommended to provide appropriate Citation and Attribution whenever technically possible with high mortality.. Is leveraged to analyze the cell cycle in high‐dimensional gene expression space mitochondrial myopathy patients be published delay! 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