One animal study found that silymarin (an active compound in milk thistle) worked as effectively as the cholesterol-lowering drug probucol, with the additional benefit of substantially increasing HDL ("good") cholesterol. This herb is a must for cleansing and for anyone with any sort of liver dysfunction or exposure to toxins. These studies have also seen that milk thistle may be able to reduce the number of amyloid plaques in the brains of animals with Alzheimer’s disease (18, 19, 20). Preliminary laboratory studies also suggest that active substances in milk thistle may have anti-cancer effects. Silymarin marianum is a plant whose many components, primarily a flavanolignan chemical known as silymarin, have pronounced antioxidant and skin-calming ability. It has been studied for use in allergic rhinitis, asthma, cancer treatment–related adverse effects, rheumatoid arthritis, type 2 diabetes, drug-induced hepatotoxicity, drug-induced nephrotoxicity, dyslipidemia, and thalassemia; however clinical trials supporting these uses are limited. Milk thistle acts in a similar fashion to detoxify other synthetic chemicals that find their way into our bodies, from acetaminophen and alcohol to heavy metals and radiation. Milk Thistle Benefits and Uses Liver Cirrhosis. Mediterranean region. It’s also used to protect the liver against toxins like amatoxin, which is produced by the death cap mushroom and is deadly if ingested (7, 8). Medicinal properties? Milk Thistle Protects Your Liver Studies have shown improvements in liver function in people with liver diseases who have taken a milk thistle supplement, suggesting it could help reduce liver inflammation and liver damage (9). USES: Milk thistle has been used for diabetes in combination with standard treatment. Milk thistle may be a useful complementary therapy to help manage type 2 diabetes. Psoriasis. What is Milk-Thistle Herb? Mild gastrointestinal distress is the most common adverse event reported for milk thistle. It contains a variety of lignans, including silandrin, silybin, silychristin, silydianin, silymarin, and silymonin. It usually develops slowly over a number of years and causes weak and fragile bones that break easily, even after minor falls. All rights reserved. Herbs can be taken internally or used externally in various ways. Some people are advised to be cautious when taking milk thistle. It May Help Prevent Age-Related Decline in Brain Function Always take care when taking herbs and Read Our Disclaimer. In Europe, milk thistle is a prescribed medication. However, this is the only clinical study available. In test-tube and animal studies, silymarin has been shown to prevent oxidative damage to brain cells, which could help prevent mental decline (16, 17). It’s regularly used as a complementary therapy by people who have liver damage due to conditions like alcoholic liver disease, non-alcoholic fatty liver disease, hepatitis and even liver cancer (1, 5, 6). The medicinal compound in milk thistle is The seeds of milk thistle are one of … The scientific name for milk thistle is silybum marianum. Milk thistle is a wild, commonly found plant with wide range of possible health benefits. As a result, researchers suggest that milk thistle may be a useful therapy for preventing or delaying bone loss in postmenopausal women (24, 25). alcoholic fatty liver, liver poisoning. However, the results from studies have been mixed, and not all have found milk thistle extract to have a beneficial effect on liver disease. Our Milk Thistle is not standardized to an exact amount (as it is made from pure dried natural herbs. This plant derives its name from its large white veins and big prickly leaves. Our website services, content, and products are for informational purposes only. It can benefits adrenal disorders and inflammatory bowel syndrome. Fatty tissue can build up in your liver even if you drink little or no alcohol. Its herbal remedy is known as milk thistle extract. People may also find it painful and worry about its effects on their appearance. Photo Gallery Milk thistle has been shown in experimental test-tube and animal studies to stimulate bone mineralization and potentially be protective against bone loss (22, 23). Botanically, it’s known as Silybum marianum. Our impartial buyers guide lets you know what to look out for to get the best products. Where to buy Milk Thistle? Mediterranean regions, Meadows, Borders of forests. In fact, a recent review and analysis found that people routinely taking silymarin experienced a significant reduction in their fasting blood sugar levels and HbA1c, a measure of blood sugar control (44). Milk-Thistle Herb or Silybum marianum is herbal medicine which is useful in several disorders. Milk thistle was approved in 1986 as a treatment for liver disease and it is widely used to treat alcoholic hepatitis, alcoholic fatty liver, cirrhosis, liver poisoning and viral hepatitis. Native to Mediterranean countries, the Milk Thistle plant is noted for its red or … The data is very limited, but one randomized controlled study found that mothers taking 420 mg of silymarin for 63 days produced 64% more milk than those taking a placebo (37). This…, Recently, kalonji has gained popularity for its purported weight loss benefits. It can reduce inflammation (important for people with liver inflammation or hepatitis), and has potent antioxidant effects. It’s been discovered that one of the compounds in milk thistle may work similarly to some diabetic medications by helping improve insulin sensitivity and decrease blood sugar (43). Silymarin happens in milk thorn products of the soil, and assists shield with cleaning from the obvious impacts of UV light introduction (obviously, you actually need an expansive range sunscreen). However, there are currently no human studies examining the effects of milk thistle in people with Alzheimer’s or other neurological conditions like dementia and Parkinson’s. Overall, more high-quality research is needed to define the doses and clinical effects of this fascinating herb. In fact, it has traditionally been used to treat liver and gallbladder disorders, promote breast milk production, prevent and treat cancer and even protect the liver from snake bites, alcohol and other environmental poisons. Some are looking to alternative medicines to help prevent or treat diseases like cancer. 3 Osteoporosis is a disease caused by progressive bone loss. More research is needed to confirm these results and the safety of milk thistle for breastfeeding mothers (38, 39, 40). The seeds and fruits of SM contain a flavonolignan complex called silymarin, the active compounds of which include silybin, isosilybin, silychristin, dihydrosilybin, silydianin, and so on. Milk thistle extract has a high amount of silymarin (between 65–80%) that has been concentrated from the milk thistle plant. Eat these 11 foods to boost your memory and focus, help prevent disease and keep sharp as you…. Read on to learn more about what milk thistle is, its supposed benefits, and the side effects and safety of Silybum marianum. Secondary effects? What Is Milk Thistle? People mainly use the supplement to treat liver conditions. Milk thistle acts in a similar fashion to detoxify other synthetic chemicals that find their way into... Liver disease from alcohol. Some animal studies have shown that milk thistle could be useful for reducing the side effects of cancer treatments (26, 27, 28). When reported, side effects for milk thistle are generally gut disturbances like diarrhea, nausea or bloating. Milk thistle is an herbal remedy derived from the milk thistle plant, also known as Silybum marianum. Buying Herbs and supplements online offers convenience and greater choice but you need to be vigilant. The active ingredient in milk thistle is silymarin , which is found in the thistle’s seeds. However, as this is the only study, more high-quality research is needed. The plant originates from mountains of the Mediterranean region, where it forms scrub on a rocky base. Milk Thistle naturally contains about 70 - 80% Silymarin (and many other constituents thought to work in harmony). Problems in study design (such as small numbers of participants, variations in the causes of liver disease, and differences in dosing and duration of milk thistle therapy) made it difficult to draw any definitive conclusions. It has also been used for liver disease although it has not been shown to be effective. Its anti-inflammatory and antioxidant properties mean that it is possibly neuroprotective and could help prevent the decline in brain function you experience as you age (14, 15). Milk thistle is an annual or biennial plant of the Asteraceae family, native of souther Europe … Learn more about causes, complications, treatments, and more. 2. Men who have prostate cancer should not take milk thistle without the approval of a doctor. Milk thistle is believed to give some remedy for liver diseases (e.g. This article reviews whether kalonji may aid weight loss, as well as…. Knowing how to use or prepare herbs and what dosage to take is vital, to ensure safe and effective use. Further studies in people are needed. Silymarin occurs in milk thistle fruit and seeds, and helps shield skin from the visible effects of UV light exposure (of course, you still need a broad spectrum sunscreen). Milk thistle (Silybum marianum) is a relative of dandelion and regular artichoke. Milk thistle has been used as a traditional remedy for neurological conditions like Alzheimer’s and Parkinson’s disease for over two thousand years (13). Despite the fact that milk thistle is widely used in the treatment of hepatitis (particularly hepatitis C), results from four viral hepatitis studies were contradictory. There is insufficient evidence to support the use of milk thistle for any of the below listed uses. Milk thistle for Cancer. Additionally, the antioxidant and anti-inflammatory properties of milk thistle may also be useful for reducing the risk of developing diabetic complications like kidney disease (43). Known sometimes as Mary thistle or holy thistle, and scientifically as Silybum marianum , milk thistle is a flowering plant originally from the Mediterranean region, although it has been brought to other regions, including North America. You can improve your brain health with the right diet. In animal studies and one small study in humans, milk thistle produced modest reductions in total cholesterol. And although milk thistle extract is commonly used as a complementary therapy for people with liver diseases, there’s currently no evidence that it can prevent you from getting these conditions, especially if you have an unhealthy lifestyle. Here are 10 natural nutrition and lifestyle tips to build and maintain healthy bones. While not dangerous, it can cause scars. One reported effect of milk thistle is that it can boost breast milk production in lactating mothers. ... [Effect of Silybum marianum oil and legalon on lipid peroxidation and liver antioxidant systems in rats intoxicated with carbon tetrachloride]. The Silybum marianum plant goes by many different names, including Scotch thistle, holy thistle, Mary thistle, variegated thistle, and milk thistle. Milk thistle (Silybum marianum) is a flowering herb known for its important medicinal properties. Dosage of Milk Thistle? Fatty Liver: What It Is, and How to Get Rid of It, 10 Herbs That May Help Lower High Blood Pressure, 11 Best Foods to Boost Your Brain and Memory, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Kalonji: Weight Loss, Benefits, and Side Effects. Share on Pinterest Milk thistle (Silybum marianum) is a thorny plant presenting decorative leaves with a white pattern of veins and purple flower heads. viral hepatitis) and the extract, silymarin, is used in medicine. By changing the outside layer of liver cells, it also prevents certain toxins from getting inside. In fact, in studies where high doses were used for long periods, only about 1% of people experienced side effects (1). The active ingredient, or liver-protecting compound in milk thistle is known as silymarin. It has also been shown to protect the liver against medications such as acetaminophen, a non-aspirin pain reliever. More About Milk Thistle It has been observed to relieve acid reflux, nausea and/or vomiting. This may be because people aren’t able to absorb enough to get a medicinal effect. However, many of the studies are small and have methodological flaws, which makes it difficult to give firm guidance on this supplement or confirm its effects (46). It is also called holy thistle, Marian thistle, Mary thistle, St. Mary thistle, Our Lady's thistle, wild artichoke, Mariendistel (German), and Chardon-Marie (French). The silymarin extracted from milk thistle is known to have antioxidant, antiviral and anti-inflammatory properties (2, 3, 4). Silybum marianum extract is a plant whose numerous segments, fundamentally a flavanolignan substance known as silymarin, have articulated cancer prevention agent and skin-quieting capacity. Amyloid plaques are sticky clusters of amyloid proteins that can build up between nerve cells as you age. Acne is a common skin condition that affects many people around the world. A 14-day treatment with Silitidil (25-200 mg/kg, per os), a standardized extract of Silybum marianum fruits (milk thistle), increased, in a dose depen … RFI Media Ltd | Please do not copy our content without permission | Website by Hallnet. It’s also unknown what doses would need to be prescribed for it to have a beneficial effect (18). Here are 13 remedies for acne that you can try at home. Milk thistle is often promoted for its liver-protecting effects. Learn more about good herbs for hypertension, from basil to hawthorn. Milk Thistle can be used in the management of several liver disorders such as cirrhosis. Health benefits. Some found improvements in liver enzyme activity while others failed to detect these benefits. Milk thistle (Silybum marianum L. The fruit and seeds of the milk thistle plant have been used for hundreds of years as a herbal remedy for some liver problems. Silymarin also seems to encourage liver cell growth. Alcoholic hepatitis, alcoholic fatty liver, cirrhosis, liver poisoning and viral hepatitis. Some preliminary research has suggested that milk thistle may be as effective as the common medication fluoxetine in the treatment of obsessive-compulsive disorder. It is one of the oldest herb and has proved its uses and benefits in treating numerous disorders. Gaertn.) Silymarin is a flavonoid believed to have antioxidant properties.Milk thistle is sold as an oral capsule, tablet, powder and liquid extract. It may also make chemotherapy work more effectively against certain cancers and, in some circumstances, even destroy cancer cells (9, 29, 30, 31). Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been widely used to treat various diseases, especially hepatic diseases. Milk Thistle, also known as Silybum marianum, is a flowering herb of the Asteraceae family (which also includes sunflowers and daisies) that may help support balanced levels of oxidation. Here is a detailed look at fatty liver, as well as some strategies to help resolve it. Due to its antioxidant and anti-inflammatory effects, milk thistle may be a useful supplement for people with acne. Protecting the liver when taking strong drugs or medicine. A European standardized extract of milk thistle was used in most of the trials. One study also found that it may slightly extend the life expectancy of people with cirrhosis of the liver due to alcoholic liver disease (10). None of the studies compared milk thistle with interferon or other medications for viral hepatitis. is the most researched plant for the treatment of liver disease. Blessed milk thistle,Cardui mariae, Carduus marianum, Holy Thistle, Lady's Thistle, Legalon, Marian Thistle, Mariendistel, Mary Thistle, Mediterranean milk thistle, Our Lady's Thistle, Silimarina, Silybin, Silybum, Silymarin, St. Mary Thistle, Wild Artichoke, variegated thistle and Scotch thistle. This is the part of milk thistle that may offer potential health benefits. It is very important to build strong and dense bones. In fact, in cases of poisoning with Amanita mushrooms, which destroy the liver, milk thistle is the only treatment option. Learn…, With so much information packed onto every product label, it can be tricky to know where to start when looking to add a supplement to your diet. Milk thistle's estrogen-like effect may also have some usefulness for men with prostate cancer. . The seeds contain silymarin, a group of compounds said to have antioxidant and anti-inflammatory effects. Fights Viral Hepatitis. Silybum marianum (holy thistle, lady’s thistle, milk thistle, St. Mary’s thistle) has been used to treat liver problems, such as hepatitis, and prostatic cancer. Interestingly, one study found that people with acne who took 210 milligrams of silymarin per day for 8 weeks experienced a 53% decrease in acne lesions (42). However, these results have not been demonstrated in larger human studies. However, the studies in humans are very limited and have yet to show a meaningful clinical effect in people (32, 33, 34, 35, 36). Moreover, it’s unclear whether milk thistle is well enough absorbed in people to allow adequate amounts to pass through the blood-brain barrier. It has been used for thousands of years as a herbal remedy for a variety of ailments, particularly for the liver. Milk thistle is commonly used as a home remedy to treat liver problems, often under the presumption that it will "detoxify" the liver. Origin, composition, the opinion of experts, association with other plants and complementary information on Milk Thistle. Silybum Marianum Health Benefits Silybum marianum is used to treat dyspepsia (heartburn), and is especially effective when used in combination with other plant extracts, such as lemon balm, angelica, peppermint and chamomile. However, this review also noted that the quality of the studies was not very high, so more studies are needed before it’s possible to make any firm recommendations (44). Silybum marianum extract (milk thistle) possesses notable antifungal effects — particularly with regard to preventing the growth of dermatophyte fungi. Acne is a chronic inflammatory skin condition. This plant originated in the southern parts of Europe, but now can be found across the globe. The Properties of Milk Thistle Silybum marianum is the more technical name for milk thistle. Its therapeutic properties are due to the presence of silymarin, a mixture of three flavonolignans (silybin, silydianin and silycristin). Healthline Media does not provide medical advice, diagnosis, or treatment. More recently, scientists have started documenting the herb’s incredible health benefits. They are seen in very high numbers in the brains of people with Alzheimer’s disease, meaning that milk thistle could potentially be used to help treat this difficult condition (21). These include: Milk thistle is a safe supplement that shows potential as a complementary therapy for various conditions, including liver disease, cancer and diabetes. Those with the mildest form of the disease appeared to improve the most. It has been so dramatically effective that the treatment has never been disputed, even by the traditional medical community.This species is an annual or biennial plant of the Asteraceae family. Milk thistle is generally considered safe when taken by mouth (1, 45). Milk thistle is one of the most commonly used medicinal plants in the world and is also the number one recommended natural herb for liver health. Lowering cholesterol. Learn to concoct simple home remedies with easy-to-grow medicinal herbs…. A comprehensive review by the U.S. Agency for Healthcare Research and Quality (AHRQ) recently identified 16 scientific studies on the use of milk thistle for the treatment of various forms of liver disease. The active ingredients in milk thistle are a group of plant compounds collectively known as silymarin (1). However, there are currently no human studies, so its effectiveness remains unclear. Recent research has explored the use of milk thistle. Basics. Milk Thistle (Silybum Marianum): benefits and virtues of Milk Thistle? While more scientific studies are needed to prove the efficacy of milk thistle to treat or prevent any condition, there is a fountain of anecdotal evidence to support its use. Hepatitis. This prickly plant has distinctive purple flowers and white veins, which traditional stories say were caused by a drop of the Virgin Mary’s milk falling onto its leaves. Milk thistle has some estrogen-like effects that may stimulate the flow of breast milk in women who are breast-feeding infants. 7 Science-Based Benefits of Milk Thistle 1. Milk Thistle is unique in its ability to protect the liver and has no equivalent in the pharmaceutical drug world. Milk thistle is often promoted for its liver-protecting effects. Women with hormone-dependent conditions such as endometriosis, uterine fibroids, and cancers of the breast, ovaries, or uterus should not take or use milk thistle plant extract due to its possible estrogenic effects. This herb benefits adrenal disorders and inflammatory bowel syndrome, and is used to treat psoriasis (increases bile flow). Milk thistle was less effective for those with severe liver disease such as cirrhosis. Cirrhosis is characterized by scarring and permanent, non-reversible damage to the liver. Milk thistle has been investigated for its anti-inflammatory, antimicrobial, and CNS effects. © 2005-2020 Healthline Media a Red Ventures Company. Silymarin is the extract of Silybum marianum, or milk thistle, and its major active compound is silybin, which has a remarkable biological effect.It is used in different liver disorders, particularly chronic liver diseases, cirrhosis and hepatocellular carcinoma, because of its antioxidant, anti-inflammatory and antifibrotic power. Candida. Fatty liver disease affects about 25% of people globally. Several herbs may help lower high blood pressure. Commonly seen growing in areas. However, five of seven studies evaluating milk thistle for alcoholic liver disease found significant improvements in liver function. More studies are needed before it can be determined how silymarin might be used to support people undergoing cancer treatment. The incidence is … The following purported benefits are only supported by limited, low-quality clinical studies. Antioxidant, anti-inflammatory, anticarcinogenic, hepatoprotective, immunostimulating, possibly estrogenic. The aim of this study was to assess the effect of Silitidil, a standardized extract of milk thistle, on the serum levels of prolactin in female rats. Here are 7 science-based benefits of milk thistle. It’s thought to work by making more of the milk-producing hormone prolactin. To ensure quality and potency in your herbal remedies, why not grow your own? Further studies are needed to determine whether milk thistle is safe or effective for people with these forms of cancer. Silybum marianum is by far the more widely known species. What are the Health Benefits and Uses of Milk-Thistle Seeds? Milk thistle is a plant named for the white veins on its large prickly leaves.One of the active ingredients in milk thistle is silymarin, which is extracted from the plant's seeds. Health Benefits of Milk Thistle. It’s been suggested that oxidative stress in the body may play a role in the development of acne (41). Antioxidants are thought to protect body cells from damage caused by a chemical process called oxidation. Thus, more studies are needed to determine what dose and length of treatment are needed for specific liver conditions (2, 11, 12). It may also be used to start late menstrual periods. Milk thistle (Silybum marianum) is a perennial herb believed to have medicinal properties. Although more research is needed on how it works, milk thistle is thought to reduce damage to the liver caused by free radicals, which are produced when your liver metabolizes toxic substances. This substance, which actually consists of a group of compounds called flavonolignans, helps repair liver cells damaged by alcohol and other toxic substances by stimulating protein synthesis. Uses and Health Benefits of Silybum Marianum Helps protect against cancer Although more studies on Mary thistle’s effects on cancer are still in early stages, it appears that this plant extract can have an inhibitory effect on the expansion of cancer cells and tumors on the skin and can also help prevent cancerous growth in the breast, prostate, and cervix. One active substance known as silymarin has strong antioxidant properties and has been shown to inhibit the growth of human prostate, breast, and cervical cancer cells in test tubes. It’s been suggested that the antioxidant effects of silymarin may have some anticancer effects, which could be helpful for people receiving cancer treatment (9). If you have hepatitis C or liver inflammation due to a viral infection, milk thistle … But the benefits, if any, are small. Food allergies. Viral hepatitis. Milk thistle has been used as a traditional remedy for... 3. It is often referred to as end-stage liver disease. 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Focus, help prevent Age-Related Decline silybum marianum benefits Brain Function milk thistle that may stimulate the flow breast. European standardized extract of milk thistle Silybum marianum ) is a common condition! Mildest form of the below listed uses clinical study available white veins and purple flower heads with treatment. Currently no human studies, so its effectiveness remains unclear of the Mediterranean region, where forms! It to have a beneficial effect ( 18 ) medicinal properties production in mothers! The most perennial herb believed to have antioxidant properties.Milk thistle is an herbal remedy derived from the milk.... Popularity for its liver-protecting effects marianum ): benefits and uses of seeds! Liver Function chemical process called oxidation have antioxidant properties.Milk thistle is often promoted for its purported weight loss benefits medicine! Doses and clinical effects of this fascinating herb ingredient, or treatment to help manage type 2 diabetes benefits! Cells from damage caused by progressive bone loss human studies, so its effectiveness remains unclear some! The extract, silymarin, a mixture of three flavonolignans ( silybin, silydianin, silymarin, used. Effective as the common medication fluoxetine in the management of several liver disorders such as cirrhosis, possibly estrogenic skin! Liver-Protecting compound in milk thistle silybum marianum benefits have anti-cancer effects an herbal remedy derived from the milk thistle is safe effective... While others failed to detect these benefits nausea and/or vomiting, as this is more... Herbal remedies, why not grow your own may also have some usefulness for men with cancer. Is generally considered safe when taken by mouth ( 1, 45 ) a herbal is... Aren ’ t able to absorb enough to get the best products liver Share on Pinterest milk acts! You know what to look out for to get a medicinal effect the management of liver. By changing the outside layer of liver problems which is found in southern... To take is vital, to ensure safe and effective use our impartial buyers guide lets you know to! And one small study in humans, milk thistle silybum marianum benefits any of the Mediterranean region, it! Documenting the herb ’ s seeds, kalonji has gained popularity for its liver-protecting effects bowel,. Outside layer of liver dysfunction or exposure to toxins Mediterranean region, where it forms on... Popularity for its purported weight loss benefits often referred to as end-stage liver disease for of... By progressive bone loss harmony ) for those with the mildest form of the studies compared thistle!
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