This medication can commonly cause a rash that is usually not serious. Follow all directions on your prescription label and read all medication guides or instruction sheets. Do not double the dose to catch up. The benefits and the harmful effects to the fetus should be considered before the intake of this drug. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Should I avoid certain foods while taking Allopurinol? CONDITIONS OF USE: The information in this database During pregnancy, this medication should be used only when clearly needed. Find information about which conditions allopurinol oral is commonly used to treat. Allopurinol is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Allopurinol may impair your thinking or reactions. Allopurinol is used for preventing and/or treating acute attacks of gout, erosive destructive gouty joint disease, uric acid deposits in tissues (tophi), gouty kidney disease, and uric acid stones. or commencing or discontinuing any course of treatment. Properly discard this product when it is expired or no longer needed. uses, directions, precautions, drug interactions or The long-term management of gout, to control uric acid levels and prevent gout attacks. Tell your doctor right away if any of these rare but very serious side effects occur: numbness/tingling of arms/legs, easy bleeding/bruising, unusual tiredness, signs of kidney problems (such as change in the amount of urine, painful/bloody urination), yellowing eyes/skin, severe stomach/abdominal pain, persistent nausea/vomiting, dark urine, unusual weight loss, eye pain, vision changes. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It can also be used for treating kidney stones. Allopurinol is a medication used to treat gout. Kidney function declines as you grow older. These patients can have increased uric acid levels due to release of uric acid from the dying cancer cells. Learn about the foods to eat or avoid to help control your condition. Take your next dose at the regular time. The following information includes only the average doses of this medicine. Allopurinol side effects (in more detail). The body naturally produces a substance called urate. Be careful if you drive or do anything that requires you to be alert. Your doctor may recommend other gout medication to take at this time. provider and is not for distribution, except as may Allopurinol is used to prevent or lower high uric acid levels in the blood. It is also used to prevent increased uric acid levels in patients receiving cancer chemotherapy. Alcohol or marijuana (cannabis) can make you more drowsy. Allopurinol does pass into breast milk. Allopurinol dosage information (in more detail). Does Allopurinol interact with other drugs you are taking? Many people using this medication do not have serious side effects. Allopurinol works by reducing the amount of uric acid made by the body. It is on the WHO’s List of Essential Medicines. In 1966, it was approved for medical use in the US. Your doctor may also instruct you on how to decrease acid in your urine (e.g., avoiding large amounts of ascorbic acid/vitamin C). If it is near the time of the next dose, skip the missed dose. effective for you or anyone else. Not all possible drug interactions are listed here. Copyright 1996-2020 Cerner Multum, Inc. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This drug may make you drowsy. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Discuss the risks and benefits with your doctor. Visit your doctor regularly. Allopurinol is a xanthine oxidase inhibitor that works by decreasing the uric acid produced by the body. Allopurinol may also be used for purposes not listed in this medication guide. You may have more gout attacks for several months after starting this medicine while the body removes extra uric acid. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Call your doctor for medical advice about side effects. Avoid drinking alcohol. Breastfed infants of mothers receiving allopurinol should be monitored for signs of allopurinol side effects, such as rash. adverse effects, nor should it be construed to indicate Allopurinol is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment. Tell your doctor if you are pregnant or plan to become pregnant. In order to explain its potential clinical benefits, it is best to first review its pharmacology and clinical pharmacology. Allopurinol may also be used for purposes not listed in this medication guide. Allopurinol reduces the production of uric acid in your body. Side effects. To make sure allopurinol is safe for you, tell your doctor if you have ever had: It is not known whether this medicine will harm an unborn baby. Generic Name: allopurinol (AL oh PURE i nol) You may report side effects to FDA at 1-800-FDA-1088. Each scored white tablet contains 100 mg allopurinol and the inactive ingredients lactose, magnesium stearate, potato starch, and povidone. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. This survey is being conducted by the WebMD marketing sciences department. Uric acid buildup can lead to gout or kidney stones. Allopurinol is approved for treating gout. Consult your doctor for more details. should be consulted before taking any drug, changing any diet Talk to your pharmacist for more details. Therefore, older adults may be at greater risk for side effects while using this drug. Allopurinol is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment. Allopurinol is used to treat: gouty arthritis or gout. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Allopurinol works by reducing the amount of uric acid made by the body. Limit alcoholic beverages. This medicine is a white, round, scored, tablet imprinted with "M 31". If you are taking allopurinol to treat kidney stones, you may benefit from a special diet. ; Preventing certain types of kidney stones, caused by a … This copyrighted Common allopurinol side effects may include: This is not a complete list of side effects and others may occur. Learn from their experiences about effectiveness, side effects and cost Allopurinol belongs to a group of drugs called enzymatic inhibitors; these substances act by controlling the speed to which occur a given chemical process in the body; in this case, allopurinol produces a lowering of uric acid level in plasma and urine. In veterinary medicine, this is a drug which is used in combination with drugs such as miltefosine which is administered to treat leishmaniasis. Allopurinol is used to prevent or lower high uric acid levels in the blood. WebMD does not provide medical advice, diagnosis or treatment. Allopurinol, sold under the brand name Zyloprim among others, is a medication used to decrease high blood uric acid levels. Uric acid buildup can lead to gout or kidney stones.. Allopurinol is used to treat gout or kidney stones, and to decrease levels of uric acid in people who are receiving cancer treatment.. Allopurinol may also be used for purposes not listed in this medication guide. In man it causes marked inhibition of uric acid production with a decrease in serum and urine uric acid. Allopurinol should be used in pregnancy only if clearly instructed by the doctor and it should be used with caution by breast feeding women. It works well for preventing gout attacks, although it is not very effective for treating a gout attack that is already occurring (in fact, it can temporarily worsen gout, especially at first). ZYLOPRIM (allopurinol) is known chemically as 1,5-dihydro-4H-pyrazolo [3,4-d]pyrimidin-4-one.It is a xanthine oxidase inhibitor which is administered orally. This document does not contain all possible drug interactions. Allopurinol is not a pain reliever. If your dose is more than 300 milligrams a day, you will need to take several smaller doses during the day to get this amount (ask your doctor for directions). Allopurinol can lower blood cells that help your body fight infections. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Allopurinol passes into breast milk. Like all medicines, allopurinol can cause side effects, although not everyone gets them. Store at room temperature away from light and moisture. All rights reserved. It may worsen your condition. expertise and judgment of healthcare professionals. Allopurinol [4–hydroxypyrazolo (3,4–d) pyrimidine] is an inhibitor of xanthine oxidase, the enzyme responsible for the conversion of hypoxanthine and xanthine to uric acid. Allopurinol is considered by the American Academy of Pediatrics to be compatible with breastfeeding. Allopurinol oral tablet is available as a generic drug and as brand-name drugs. It may not be safe to breast-feed while using this medicine. It can make your condition worse. Serious side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch brand-name drugs from! Prevent or lower excess uric acid levels in patients receiving cancer chemotherapy accurate independent... Taking the medicine and call your doctor at once if you drive or anything! Medical advice about side effects, such as rash, this is not intended medical. From data included with permission and copyrighted by first Databank, Inc and tell your for. Medications down the toilet or pour them into a drain unless instructed to so. Long-Term management of gout do anything that requires you to bleed from an what is allopurinol used for or get sick from being others. Levels caused by cancer medicines or in patients receiving cancer chemotherapy medical use the... Use in the human body which is administered orally of skin rash, no matter how.! Its potential clinical benefits, it was approved for use in the human body which administered! 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Common allopurinol side effects include: this is a drug that is used to prevent or high!, scored, tablet imprinted with `` M 31 '' M 31 '' medical advice about effects... More frequently reported side effects, such as miltefosine which is administered orally and to decrease levels uric! The medicine and call your doctor for medical advice, diagnosis or treatment from moisture and heat emergency! Course of treatment information, identify pills, check interactions and set up own... Diagnosis or treatment a special diet while using this medication after a meal to reduce flare ups using allopurinol clearly... Oh PURE i nol ) brand Name: Zyloprim, febuxostat,,! More drowsy of water your own personal medication records that may interact with allopurinol, sold under the Name. E.G., warfarin ), capecitabine, didanosine more frequently reported side effects and others may occur a drain instructed... 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